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if p.lower == "no" or "n":

if p.lower() == "no"  or  p.lower() == "n":

# This works!
import random
from random import randint

n = ['no', 'n', 'No', 'N', 'NO']
y = ['yes', 'y', 'Yes', 'Y', 'YES']
x = random.randint(1,100)

print("Guess a number between 1 and 100.")

active = True
while active:
	guess = int(input(""))
	if guess == x:
		print("Congratulations! Would you like to play again?")
		play_again = input("")
		if play_again in n:
			print("Thanks for playing!")
			active = False
		elif play_again in y:
			print("Guess a number between 1 and 100.")
		
		
	elif guess < 1 or guess > 100:
		print("You have to choose a number between 1 and 100.")
		print("Please guess again.")
	elif guess < x:
		print("Please choose a higher number.")
	elif guess > x:
		print("Please choose a smaller number.")