with open('words.txt', 'r') as read:
    line = read.readlines()

def make_anagram_dict(line):
    word_list = {}

    for word in line:
        word = word.lower()
        key = ''.join(sorted(word))
        if key in word_list and len(word) > 5 and word not in word_list:
            word_list[key].append(word)
        else:
            word_list[key] = [word]

    return word_list

if __name__ == '__main__':
    word_list = make_anagram_dict(line)

    for key, words in word_list.items():
        if len(words) >:
            print('Key value' + ' '*len(key) + '|     words')
            print(key + ' '*len(key) + ':' + str(words))
            print('---------------------------------------------')

Output:
Key value       |     words

hortwy       :['worthy\n', 'wrothy\n']
---------------------------------------------