How to convert 4 bytes to an integer ?

[Jeff_t]

I too am using python 3 with the following, for the test I used a list and filled it with the four byte values you have been transmitting. It works with a RS232 transmission also.

b=[254,15,0,0]
  value = int.from_bytes(b, byteorder='little', signed=False)    
  print(value)  

which prints 4094