python coding to run file

[NSR115]

Please help in the python command.

file location is below which has to be open and run command than save.
‪I:\new\ACR\FINAL AUTO ACER.xlsx

I want the python command to open the above file than press (ALT+F5) which is refress command
than wait for 15 seconds then save the same file and close.

thanks in advance.