Ignore character in if statement

[Fizo]

Hello, I am writeing my cipher algorithm and I've problem with my XOR algorithm implementation. How I can ignore character for example comma in IF statement but it's was still been in string. Thanks in advance for help.

for i in range(len(klucz)):
                for x in cipher.find(s,","):
                    if(key_i == x):
                        main_cipher.insert(x,",")
                        #print("Dodaje przecinek na indexie: "+str(x))
                if(key[key_i] != s[key_i]):
                        main_cipher.append("1")
                        #print("Dodaje 1 na indexie => "+str(key_i)+" z porówniania cyfry klucza: "+str(klucz[key_i])+", oraz tekstu: "+str(s[key_i]))
                        key_i += 1
                else:
                        main_cipher.append("0")
                        #print("Dodaje 0 na indexie => "+str(key_i)+" z porówniania cyfry klucza: "+str(klucz[key_i])+", oraz tekstu: "+str(s[key_i]))
                        key_i += 1