python GUI - which to use ?

[metulburr]

PyQt4 and PyQt5 both work for python.
The change quoted from google searching

The main change from Qt4 to Qt5 and hence from PyQt4 to PyQt5 is the rearrangement of certain classes so that the Qt project is scalable and generates a smaller executable.

The QtGui library was divided into 2 submodules: QtGui and QtWidgets, in the second only the widgets, namely QMainWindow, QPushButton, etc. And that is the change you must make:

That is definitely an option for you since you are familiar with it.

I would use WxPython Phoenix if i was to create a GUI. But that is half because i am more familiar with that than pyqt.