INA219 with PI4

[DeaD_EyE]

I guess it's a permission error.

# shell, not Python
usermod -G i2c -a USERNAME
# then reboot or open a new login shell with:
# su - USERNAME

You can check your memberships in groups with the command id.

After this action, the user should be able to write to the i2c bus.
If you try next time to access as normal user to a serial port, you'll get again an error.
In this case, you should add the user to the group dialout.