Which package installation methods to use inside a python virtual environment?

[snippsat]

You only use sudo or elevated permissions when you want to install stuff for the global, system-wide Python installation.
A bonus is that virtualenv does not need elevated permissions.

It's best to always try to avoid sudo pip install,also for pip usage on OS without virtualenv.
Instead, consider using pip install --user,or pyenv as i use.
With pyenv OS installation so is Python always in user mode and never need for sudo pip install.

When you run pip with sudo, you run setup.py with sudo.
In other words, you run arbitrary Python code from the Internet as root.
If someone puts up a malicious project on PyPI and you install it, you give an attacker root access to your machine.
Prior to some recent fixes to pip and PyPI, n attacker could also run a man in the middle attack to inject their code when you download a trustworthy project.