Python3 - serial port reload

[parovelb]

I am having a problem reading/writing to a serial port after the port has been disconnected. I can successfully connect to my device and communicate with it. Then I execute a voluntary disconnect, I reopen the port but I am unable to write/read. Is it possible to reload the port without restarting the script?

The ttyACM* port has an active symlink connection in /etc/udev/rules.d/99-usb-serial.rules:

SUBSYSTEM=="tty", ATTRS{idVendor}=="1234", ATTRS{idProduct}=="5678", SYMLINK+="ttyACM_dev0"

To open the port:

#!/usr/bin/python3 python3
# -*- coding: utf-8 -*-

import serial
global ser0

# open the dev0 serial port
try:
    ser0 = serial.Serial("/dev/ttyACM_dev0")
    ser0.isOpen()
except serial.serialutil.SerialException:
    ser0 = None
else:
    print (ser0.name, 'port opened successfully')

The error usually is like:

Error:
ser1.flushOutput() # Clear output buffer
   File "/usr/lib/python3/dist-packages/serial/serialutil.py", line 587, in flushOutput
     self.reset_output_buffer()
   File "/usr/lib/python3/dist-packages/serial/serialposix.py", line 604, in reset_output_buffer
     termios.tcflush(self.fd, termios.TCOFLUSH)
 termios.error: (5, 'Input/output error')