Setting GPIO on Raspberry PI using a function

[nilamo]

This is unrelated to your code, but all those functions look veeeeery similar to me, so I'd probably just turn them all into a single function.  Maybe something like:

def set_pins(first=True, second=True, third=True):
  GPIO.output(17, GPIO.HIGH if first else GPIO.LOW)
  GPIO.output(27, GPIO.HIGH if second else GPIO.LOW)
  GPIO.output(22, GPIO.HIGH if third else GPIO.LOW)

Then, maybe I'd have some helper functions for each combination:

MUX1shift1_Y0 = lambda: set_pins(False, False, False)
# etc

The helpers could probably all be generated in a loop, instead of copy-paste (but I'm a little too busy to think that hard right now, lol).

As to your actual question, what does this mean?

I need the GPIO's to be returned from the function

Given one of the combinations, what, exactly, should be the return value?