Running python code meant for Notepad++ plugin independently

[greektranslator]

Please excuse my ignorance, but I am trying to run this code: https://python-forum.io/Thread-Matching-...ace-script

with open('C:/fix.txt') as f:
    for l in f:
        s = l.split()
        editor.replace(s[0], s[1])

independently from Notepad++ (as it hangs on large texts). I have Python 3.5 installed on Windows. How would I have to edit that code to define the file on which the replacements must be made? Currently, only the file with the replacement set is defined.