Creating a python exe (win) to run on Mac

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PyInstaller Manual

PyInstaller is tested against Windows, Mac OS X, and GNU/Linux.
However, it is not a cross-compiler: to make a Windows app you run PyInstaller in Windows;
to make a GNU/Linux app you run it in GNU/Linux, etc.

One the easiest way if on Windows is to use VirtualBox,follow a tutorial.
Then use Pyinstaller there to make executable for Mac.