Find and delete above a certain line in text file

[snippsat]

StringIO as i used is not needed when read from a file.
It make the string i copied from you post act like a file-like object in memory..

import pandas as pd

df = pd.read_csv("data.csv", names=["Date", "Time", "Comment"])
df['DateTime'] = pd.to_datetime(df["Date"] + df["Time"])
mask = (df['DateTime'] >= '2022-03-08 16:15:00')
df_new = df.loc[mask]
#df_new = df_new.drop(columns=['DateTime'])
df_new = df_new.drop(columns=['Date', 'Time'])
print(df_new)

Output:
          Comment            DateTime
6    String Value 2022-03-08 16:15:00
7    String Value 2022-03-08 16:15:00
8    String Value 2022-03-08 16:15:00
9    String Value 2022-03-08 16:15:00
10   String Value 2022-03-08 16:17:00
11   String Value 2022-03-08 16:17:00

Line 7 uncomment:

Output:
      Date      Time        Comment
6   3/8/22   4:15 PM   String Value
7   3/8/22   4:15 PM   String Value
8   3/8/22   4:15 PM   String Value
9   3/8/22   4:15 PM   String Value
10  3/8/22   4:17 PM   String Value
11  3/8/22   4:17 PM   String Value

[deanhystad]

I am guessing this is a typo:

mask = (df['DateTime'] > '2022-03-08 16:06:00') & (df['DateTime'] >= '2022-03-08 16:15:00')

Any datetime > '2022-03-08 16:06:00' is also >= '2022-03-08 16:15:00'.
Maybe it was going to be an example of a start and end datetime.

mask = (df['DateTime'] > '2022-03-08 16:06:00') & (df['DateTime'] <= '2022-03-08 16:15:00')

[snippsat]

Maybe it was going to be an example of a start and end datetime.

Yes that was the idea,thx for the correction.