Getting a "Cannot be Opened"" error Message

[buran]

This is example how not to implement try/except - you catch all exceptions and provide a message that's not relevant.

you have s0xWins note that second character is zero, not o on line

average_win = int(s0xWins/numberOfGames) * 100

So your actual error is that s0xWins is used before assignment.

You should avoid using such catch-all exception clause, especially when you don't pass on the actual error description.