A quick question

[teczone]

Basic idea,can use !=(not equal).
Then loop run until guessed the secret number,so no need to break out of the loop.

import random

secret_number = random.randint(1, 100)
tries, guess = 0, 0
while guess != secret_number:
   guess = int(input("Take a guess: "))
   # Lower or Higer(if,elif) when secret_number is guess the loop end

Actually, you didn't understand very well:
I don't know if you know the game of the right price, but in any case if you put a lower number than the right number, it should say whether it's smaller or larger.