Learned Python Basics, what now?

[snippsat]

Is it possible to build a website with Python without the use of one of the Python Frameworks?

Yes,but in reality not(if not want to make new a Framework)
Short history CGI the old way did many understand that could not way be for web in future for Python.

So there was an effort to write WSGI(an all Python solution).
Today all Python Frameworks is build on top of WSGI.
So could make website with pure WSGI,but it will be very painful

Flask is thin layer above WSGI build on top of Werkzeug(very close to WSGI) .
So eg Flask has taken over the old CGI way to work with web as you close to HTML/CSS with little overhead.

Django has a other model with a lot stuff build in and has own ORM for database.
In Flask you use plugin if need to extend as eg Flask-SQLAlchemy

FastAPI framework is the new star ✨